Dental
Advanced Bone Matrices
xCyte DBM Putty, NovioBone & Cancellous Cubes
Advanced bone matrices combine innovation with the reliability of human-derived grafts to simplify handling while promoting robust bone regeneration. Designed for complex orthopedic procedures, these matrices provide structural integrity, enhance cellular integration, and support vascularization—critical for successful bone healing and remodeling.
Your Partner In Performance-Driven Bone Regeneration
xCyte DBM Putty
Reliable Dental Bone Void Filling. Ready When You Are.
Key Benefits:
- Biobased components.
- Moldable and easy to handle.
- Sterile, single-use packaging.
- Versatile across spinal orthopedic and dental applications.
Performing a simple procedure and only need a small amount? Tackling a larger surgery and need to fill a bigger space? No problem, each formulation will be equipped with multiple volume options:
Injectable—0.5 CC, 1.0 CC, 2.5 CC, 5.0 CC and 10 CC Injectable Plus—0.5 CC, 1.0 CC, 2.5 CC, 5.0 CC and 10 CC Injectable Crunch—0.5 CC, 1.0 CC, 2.5 CC, 5.0 CC and 10 CC Paste—0.5 CC, 1.0 CC
4 Formulations To Fit Any Need
Injectable
100% human DBM with a medium viscosity biobased carrier for smooth delivery.
Injectable +
100% human DBM with human derived carrier; a 100% human product.
Injectable Crunch
DBM with cancellous chips for added structure with a medium viscosity biobased carrier.
Paste
100% human DBM with a higher viscosity biobased carrier for better graft retention.
Did You Know?
DBM was originally discovered to be osteoinductive by accident in the 1960s, when researchers noticed that demineralized bone implanted into animals triggered the unexpected formation of new bone in places bone shouldn’t normally grow. That surprise finding ended up becoming one of the foundations of modern biologics.
Regulatory Excellence and Clinical Versatility
At Noviotissue, we’ve modernized the DBM experience—with smoother handling, more formulation choice, and consistent performance. Whether you’re grafting a ridge or reinforcing a spine, DBM still matters—and now it’s better than ever.
But Why does it matter? DBM still stands out as the gold-standard in bone void surgery because it really works!
- Osteoinductive and osteoconductive.
- Derived from real human tissue.
- Backed by decades of use across orthopedic, dental, and spine surgeries.
NovioBone
In dental and oral surgery, bone loss or defects—whether resulting from extraction, trauma, cyst removal, periodontal disease, or tumor resection—pose major challenges for functional and aesthetic rehabilitation. NovioBone is a bone void filler designed to support bone regeneration and restore anatomical continuity in the jaws and oral cavity.
NovioBone offers a biocompatible, stable scaffold to:
- Reconstruct alveolar bone defects after extractions or ridge resorption
- Fill defects after cyst enucleation or tumor removal in the jaw
- Augment bone in preparation for dental implants
- Repair bone at implant sites (e.g. sinus lift, ridge augmentation)
- Support guided bone regeneration (GBR) and periodontal regenerative procedures
Its structural integrity and biological properties make it a reliable choice in reconstructive oral and maxillofacial surgery.
Advantages & Key Features:
- Biocompatible Scaffold – Offers a safe environment for bone healing, reducing risk of adverse reactions in oral tissues
- Structural Stability – Maintains space and resists collapse under soft tissue pressure
- Bone-Conductive – Encourages ingrowth of native bone into the scaffold
- Volume Customization – Available in small volumes appropriate for intraoral defects
- Ease of Handling – Designed for convenient delivery and contouring in challenging oral sites
- Long-Term Support – Durable enough to endure functional loading after graft maturation
Tips for Use:
- Prepare the recipient site by decorticating bone walls to encourage bleeding and graft integration
- Use an appropriate membrane for guided bone regeneration when indicated
- Maintain soft tissue closure without tension to protect the graft
- In implant cases, stage placement or simultaneous placement should be determined case by case
- Follow standard post-operative protocols (e.g. antibiotic prophylaxis, soft diet, oral hygiene instructions)
Cancellous Cubes
Engineered with both biological performance and clinical efficiency in mind, these allograft-based materials offer a natural scaffold that supports osteoconduction and osteoinduction. Their versatile handling properties make them suitable for use in trauma, spine, and reconstructive applications where traditional grafts may be difficult to place or shape. By combining strength with flexibility and biocompatibility, advanced bone matrices help surgeons achieve stable fixation and long-term graft incorporation, even in challenging anatomical sites.
Product Handling
Cancellous Cubes can be applied directly to the defect site. Compress the cube slightly before placement; upon exposure to blood or saline, it will expand to fill the space and conform to the surrounding bone. Secure fixation is typically achieved without additional hardware.
Versatile Bone Graft for Orthopedic Reconstruction
Cancellous Cubes are designed to meet the demands of orthopedic bone repair and regeneration. Each cube acts as a dynamic bone scaffold composed of cortico-cancellous grafts integrated with gelatin and hyaluronic acid. This combination provides excellent handling, adaptability, and biological performance in both open and minimally invasive procedures.
The compressible structure allows surgeons to easily shape and position the graft into irregular bone defects. Upon contact with blood or other physiological fluids, the cubes expand—ensuring optimal defect fill, stable placement, and intimate contact with surrounding bone. The resulting increase in porosity facilitates cellular migration, angiogenesis, and new bone formation, supporting faster and more predictable healing.
Key Features & Benefits:
- Optimized Handling: Compressible and easy to mold into complex defect geometries.
- Expandable Structure: Expands upon contact with fluid for superior fit and fixation.
- Enhanced Porosity: Promotes cellular infiltration and vascularization for improved integration.
- Cortico-Cancellous Blend: Balances strength and resorption for predictable remodeling.
- Time-Saving Application: Ready-to-use formulation—no mixing or preparation required.
Clinical Applications:
- Trauma and fracture repair
- Spinal fusion and vertebral reconstruction
- Revision arthroplasty
- Non-union and delayed union defects
- Small to medium segmental defects
Did You Know?
Cancellous cubes are so porous that they’re often compared to natural “biological sponges.” Surgeons love them because those tiny trabecular pathways act like highways for cells and blood vessels. A single cubic centimeter of cancellous bone can contain over 70 percent air space, which is one reason it integrates so well once it’s implanted.
Clinical Applications in Dentistry & Oral Surgery
- Socket Preservation / Ridge Augmentation
- After tooth extraction, NovioBone can be placed into the alveolus to preserve socket dimensions, maintain ridge volume, and minimize collapse. This enhances future implant placement or prosthetic options by preserving vertical and horizontal bone.
- Bone Defect Repair after Cyst or Tumor Removal
- Lesions such as radicular cysts, dentigerous cysts, or benign tumors often leave voids in the jawbone. NovioBone can be used to fill these defects, promoting bone regeneration and restoring the structural integrity of the jaw.
- Implant Site Preparation & Sinus Augmentation
- In cases with insufficient bone height or width, NovioBone can be used in ridge augmentation, guided bone regeneration, or sinus lift procedures. It helps create a stable, osteoconductive environment for implant placement and osseointegration.
- Ridge Augmentation (Horizontal & Vertical)
- For alveolar ridges that have undergone resorption, NovioBone can assist in building up deficient bone volume — either lateral augmentation or vertical height build-up — to allow optimal implant positioning and prosthetic outcomes.
- Periodontal Bone Regeneration
- In advanced periodontal defects, where bone support loss impairs tooth stability, NovioBone may be incorporated (often combined with membranes or growth factors) to help regenerate alveolar bone and support tooth retention.
Product Brochures
Explore our comprehensive product brochures to learn more about the features, clinical applications, and handling instructions for each offering. Whether you are seeking solutions for bone regeneration, soft tissue repair, or aesthetic enhancement, our brochures provide detailed information to help guide your selection and optimize patient care. Click below to view or download the latest brochures and discover how xCyte BioTech can support your clinical practice.
Packaging and Storage
Our allograft products are carefully packaged to protect sterility, preserve quality, and ensure confidence at the point of use. Designed for reliability from storage to the operating room, each product arrives ready for seamless integration into your surgical workflow.
Explore full packaging details, storage guidelines, and handling information on our Packaging & Storage page.
Ordering Information
Placing an order with us is designed to be simple and efficient. Our team works closely with you to ensure accurate product selection, timely delivery, and compliance with all regulatory requirements. Clear communication and dedicated support make the ordering process seamless — so you can focus on providing the best care for your patients. To begin your order, please reach out to us through our Contact Page.
Code | Description | Volume/Size | Viscosity |
XP-DBM-005 | NovioBone DBM Putty Injectable; 100% DBM with Biobased Carrier | 0.5 cc | Medium |
XP-DBM-010 | NovioBone DBM Putty Injectable; 100% DBM with Biobased Carrier | 1.0 cc | Medium |
XP-DBM-025 | NovioBone DBM Putty Injectable; 100% DBM with Biobased Carrier | 2.5 cc | Medium |
XP-DBM-050 | NovioBone DBM Putty Injectable; 100% DBM with Biobased Carrier | 5.0 cc | Medium |
XP-DBM-1000 | NovioBone DBM Putty Injectable; 100% DBM with Biobased Carrier | 10 cc | Medium |
XP-DBM-P005 | NovioBone DBM Putty Injectable Plus; 100% DBM w/ Human Carrier | 0.5 cc | Medium |
XP-DBM-P010 | NovioBone DBM Putty Injectable Plus; 100% DBM w/ Human Carrier | 1.0 cc | Medium |
XP-DBM-P025 | NovioBone DBM Putty Injectable Plus; 100% DBM w/ Human Carrier | 2.5 cc | Medium |
XP-DBM-P050 | NovioBone DBM Putty Injectable Plus; 100% DBM w/ Human Carrier | 5.0 cc | Medium |
XP-DBM-P100 | NovioBone DBM Putty Injectable Plus; 100% DBM w/ Human Carrier | 10 cc | Medium |
XP-DBM-C005 | NovioBone DBM Putty Injectable Crunch; DBM + Cancellous w/ Biobased Carrier | 0.5 cc | Medium |
XP-DBM-C010 | NovioBone DBM Putty Injectable Crunch; DBM + Cancellous w/ Biobased Carrier | 1.0 cc | Medium |
XP-DBM-H005 | NovioBone DBM Putty Paste; 100% DBM with Biobased Carrier | 0.5 cc | High |
XP-DBM-H010 | NovioBone DBM Putty Paste; 100% DBM with Biobased Carrier | 1.0 cc | High |
XP-DBM-H025 | NovioBone DBM Putty Paste; 100% DBM with Biobased Carrier | 2.5 cc | High |
XP-DBM-H050 | NovioBone DBM Putty Paste; 100% DBM with Biobased Carrier | 5.0 cc | High |
XP-DBM-H100 | NovioBone DBM Putty Paste; 100% DBM with Biobased Carrier | 10 cc | High |
BE8002FD | NovioBone, 50/50 Blend | 0.5 CC | – |
BE8003FD | NovioBone, 50/50 Blend | 1.0 CC | – |
BE8010FD | NovioBone Cancellous Cubes | 10 x 10 x 10 mm | – |